This Cell Type May Trigger Alzheimer's
Microglia are amoeba-like cells that scour the brain for injuries and invaders.
They help clear dead or impaired brain cells and literally gobble up invading microbes. Without them, we'd be in trouble.
In a normal brain, a protein called beta-amyloid is cleared away through our lymphatic system by microglia as molecular junk.
But sometimes it builds up. Certain gene mutations are one culprit in this toxic accumulation. Traumatic brain injury is another, and, perhaps, impaired microglial function.
To date, nearly a dozen genes involved in immune and microglial function have been tied to Alzheimer's.
The first was CD33, identified in 2008.
If CD33 is the yin, a gene called TREM2 is the yang.
Discovered a few years after CD33, TREM2 reins in microglial activation, returning them to their role as cellular housekeepers.
#医学生Medic[超话]##medicaltalks#
Microglia are amoeba-like cells that scour the brain for injuries and invaders.
They help clear dead or impaired brain cells and literally gobble up invading microbes. Without them, we'd be in trouble.
In a normal brain, a protein called beta-amyloid is cleared away through our lymphatic system by microglia as molecular junk.
But sometimes it builds up. Certain gene mutations are one culprit in this toxic accumulation. Traumatic brain injury is another, and, perhaps, impaired microglial function.
To date, nearly a dozen genes involved in immune and microglial function have been tied to Alzheimer's.
The first was CD33, identified in 2008.
If CD33 is the yin, a gene called TREM2 is the yang.
Discovered a few years after CD33, TREM2 reins in microglial activation, returning them to their role as cellular housekeepers.
#医学生Medic[超话]##medicaltalks#
#医学生Medic[超话]#
⭐POLYCYSTIC KIDNEY DISEASE⭐
➡️Polycystic kidney disease (PKD) is an inherited disorder in which clusters of cysts develop primarily within your kidneys, causing your kidneys to enlarge and lose function over time.
➡️Cysts are noncancerous round sacs containing fluid. The cysts vary in size, and they can grow very large. Having many cysts or large cysts can damage your kidneys .
Symptoms:
➡️High blood pressure
➡️Blood in your urine
➡️A feeling of fullness in your abdomen ➡️Increased size of your abdomen due to enlarged kidneys
➡️Headaches
➡️Kidney stones
➡️Kidney failure
➡️Urinary tract or kidney infections https://t.cn/RpzsaHS
⭐POLYCYSTIC KIDNEY DISEASE⭐
➡️Polycystic kidney disease (PKD) is an inherited disorder in which clusters of cysts develop primarily within your kidneys, causing your kidneys to enlarge and lose function over time.
➡️Cysts are noncancerous round sacs containing fluid. The cysts vary in size, and they can grow very large. Having many cysts or large cysts can damage your kidneys .
Symptoms:
➡️High blood pressure
➡️Blood in your urine
➡️A feeling of fullness in your abdomen ➡️Increased size of your abdomen due to enlarged kidneys
➡️Headaches
➡️Kidney stones
➡️Kidney failure
➡️Urinary tract or kidney infections https://t.cn/RpzsaHS
钟南山医学基金会南山跑团携手
乐跑客、爱救团给大家拜年啦！
祝大家虎年吉祥如意，虎虎生风！
祝伟大祖国早日摆脱疫情滋扰，早日把美国～国际流氓踩在脚下！
#体育##日行一善##健康#
一起运动，一起公益！
南山跑团2022线上公益迎新跑启动（徒步跑步均可，5公里起步）。
活动报名费99元将全额定向捐赠用于全民健身实施计划公益慈善事业。完赛可获得春节元素精美醒狮奖牌、南山跑团定制跑步T恤、定制姓名号码布、电子荣誉证书。
"传递南山精神、跑出健康人生！"为全民健身助力、加油！
报名链接：https://t.cn/A6ihJC5y#跑步[超话]##斯巴达勇士赛[超话]##医学生Medic[超话]#
乐跑客、爱救团给大家拜年啦！
祝大家虎年吉祥如意，虎虎生风！
祝伟大祖国早日摆脱疫情滋扰，早日把美国～国际流氓踩在脚下！
#体育##日行一善##健康#
一起运动，一起公益！
南山跑团2022线上公益迎新跑启动（徒步跑步均可，5公里起步）。
活动报名费99元将全额定向捐赠用于全民健身实施计划公益慈善事业。完赛可获得春节元素精美醒狮奖牌、南山跑团定制跑步T恤、定制姓名号码布、电子荣誉证书。
"传递南山精神、跑出健康人生！"为全民健身助力、加油！
报名链接：https://t.cn/A6ihJC5y#跑步[超话]##斯巴达勇士赛[超话]##医学生Medic[超话]#
✋热门推荐