【Nature：利用6156个人类基因组序列成功构建出人类基因组约束图谱】每个人的基因组都有数百万个基因变异，但大多数变异几乎没有影响，这使得临床医生很难根据基因差异进行医学诊断。

在一项新的研究中，由来自美国麻省总医院和布罗德研究所的研究人员领导的一个研究团队利用数万个具有全基因组序列数据的个体的基因变异模式，确定了基因组中缺乏典型变异的区域，这表明它们是进化和自然选择过程中保守的重要序列。这表明当一种基因变异出现在其中的一个区域时，它更有可能对个体的健康产生影响。相关研究结果于2023年12月6日在线发表在Nature期刊上，论文“A genomic mutational constraint map using variation in 76,156 human genomes”。https://t.cn/A6lrx0Mu

【Game Theory Based Model for Predictive Analytics Using Distributed Position Function】
#论文# #群体决策# #预测分析# #博弈论# #预测谈判#

The ability to predict the outcome of a negotiation is an important topic in various fields. This paper introduces a game theory-based approach for forecasting outcomes of negotiation and group decision-making problems and proposes an extension to the BDM model that addresses situations where actors' positions span a spectrum, thus offering increased flexibility in defining their targets.

DOI: 10.4236/ijis.2024.141002

https://t.cn/A6jhuUKv

大家好！我是湖北的脑控受害者余凤莲，脑控狗总是用脑控武器，控制家里出现大量苍蝇、蚊子，象虫、甚至蛆虫、老鼠等
家里的蚊蝇纸、灭蚊器、灭蚊水、灭蚊片等啥都不管用，满屋子全是苍蝇蚊子象虫蛆虫老鼠等。
脑控狗真是变态到极点，竟然用脑控武器控出蛆虫，爬在我手臂、腿子上
有时吃饭的时候，碗上面突然爬出个白蛆虫。
以下是英语翻译:
The following is an English translation:

Hello everyone! I am Yu Fenglian, a brain control victim from Hubei. Brain control dogs always use brain control weapons to control a large number of flies, mosquitoes, elephants, and even maggots, mice, etc. in their homes
The mosquito paper, mosquito repellent, mosquito repellent water, mosquito repellent tablets, etc. at home are useless, and the room is filled with flies, mosquitoes, insects, maggots, mice, and so on.
The brain controlled dog is really abnormal, using a brain controlled weapon to control maggots and crawl on my arms and legs
Sometimes while eating, a white maggot suddenly crawls out of the bowl.#山东工艺美术学院[超话]#