【Br J Pharmacol:补体C3可作为降低高血压肾病患者蛋白尿的新靶点】越来越多的临床疾病涉及补体系统的病理性贡献,这促使人们重新对调节这一宿主防御途径的治疗方案感兴趣。基于这些发现,制药行业已将补体系统确定为治疗各种疾病的潜在和有前景的靶点。
补体系统保护宿主免受有害微生物环境的侵害,并通过消除改变或死亡的细胞来维持组织和细胞的完整性。作为先天免疫的重要效应臂,它在获得性免疫的调节中也发挥着核心作用。因此,补体激活可能通过对先天和获得性免疫反应的影响来推动高血压的病理。
近日,来自汉堡-埃彭多夫大学医学中心的研究者们在Br J Pharmacol杂志上发表了题为“Complement component C3 as a new target to lower albuminuria in hypertensive kidney disease”的研究,该研究在高血压小鼠和男性的肾脏中发现C3表达增加。基因和治疗性C3基因敲除改善了高血压早期的蛋白尿,但没有改善动脉血压,也没有改善肾脏和心脏的损伤。https://t.cn/A6pZch1r
补体系统保护宿主免受有害微生物环境的侵害,并通过消除改变或死亡的细胞来维持组织和细胞的完整性。作为先天免疫的重要效应臂,它在获得性免疫的调节中也发挥着核心作用。因此,补体激活可能通过对先天和获得性免疫反应的影响来推动高血压的病理。
近日,来自汉堡-埃彭多夫大学医学中心的研究者们在Br J Pharmacol杂志上发表了题为“Complement component C3 as a new target to lower albuminuria in hypertensive kidney disease”的研究,该研究在高血压小鼠和男性的肾脏中发现C3表达增加。基因和治疗性C3基因敲除改善了高血压早期的蛋白尿,但没有改善动脉血压,也没有改善肾脏和心脏的损伤。https://t.cn/A6pZch1r
#四六级[超话]#
【四六级打卡】Day31#四六级一笑而过##四六级# 今天听了周思成老师的六级作文技巧课
谚语重要性题开头模板:
第一句不变 It is a truth widely accepted that ...
把谚语插在第二句话:
As a famous saying goes ,"...........'
第三句:
This proverb tells us that in order to .... we should ...
【四六级打卡】Day31#四六级一笑而过##四六级# 今天听了周思成老师的六级作文技巧课
谚语重要性题开头模板:
第一句不变 It is a truth widely accepted that ...
把谚语插在第二句话:
As a famous saying goes ,"...........'
第三句:
This proverb tells us that in order to .... we should ...
【中国与阿根廷签署共建“一带一路”合作规划】6月2日,中国和阿根廷两国政府代表在北京签署《中华人民共和国政府与阿根廷共和国政府关于共同推进“一带一路”建设的合作规划》。《合作规划》深化双方在基础设施、能源、经贸、金融、人文等领域互利合作;将进一步推进两国共建“一带一路”走深走实,为双方企业创造更多合作机遇,更好增进两国人民福祉。
Representatives of the Chinese and Argentine governments signed a cooperation plan on promoting the Belt and Road Initiative (BRI) on Friday in Beijing, according to China's National Development and Reform Commission. The two countries will deepen cooperation in the fields of infrastructure, energy, economy and trade, finance, as well as cultural exchanges according to the plan.
Representatives of the Chinese and Argentine governments signed a cooperation plan on promoting the Belt and Road Initiative (BRI) on Friday in Beijing, according to China's National Development and Reform Commission. The two countries will deepen cooperation in the fields of infrastructure, energy, economy and trade, finance, as well as cultural exchanges according to the plan.
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