蜗之壳Snail-Shell带来了砂之家事务所姐妹俩的可动手办,她们分别是姐姐时樱以及妹妹砂织,整体采用了1/12的比例。这两款产品最大的卖点就是采用了可拆卸服装的设计,同时胸部零件还用到了硅胶材质。姐姐 砂之家-时樱官方定价568元,妹妹 砂之家-砂织官方定价589元,预计2023年第三季度出货!#涛哥测评[超话]#
#飙上碎碎# Freshwater leeches‘ taste for snails could help control snail- borne disease (More research is needed before leeches becomes snail biocontrol)
Leeches might seem like relics of a bygone age of medicine ,but they haven't outlived their usefulness to people yet . The freshwater leech Helobdella austinensis can eat its weight in snails everyday,suggesting that leeches could used to control freshwater snail population — and the host of disease they carry ,researchers report April12 in Biology Letters . By Bethany Brookshire
#ScienceNews#
Leeches might seem like relics of a bygone age of medicine ,but they haven't outlived their usefulness to people yet . The freshwater leech Helobdella austinensis can eat its weight in snails everyday,suggesting that leeches could used to control freshwater snail population — and the host of disease they carry ,researchers report April12 in Biology Letters . By Bethany Brookshire
#ScienceNews#
PNAS:中南大学陶永光教授团队揭示可作为潜在诱导肿瘤细胞铁死亡的最新靶标
铁死亡是一种铁依赖性氧化,非凋亡形式的调节细胞死亡,由氧化还原稳态的破坏引起。最近的研究揭示了调节铁死亡的复杂细胞网络。GINS4是真核G1 / Scell循环的启动子,作为DNA复制开始和伸长的调节剂,但对其对铁死亡的影响知之甚少。
4月5日,中南大学基础医学院肿瘤研究所陶永光团队在知名期刊《Proceedings of the National Academy of Sciences of the United States of America》上发表研究论文“GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail”,研究发现GINS4参与了肺腺癌铁死亡的调控。在研究探讨DNA复制基因在LUAD中的作用时,研究人员发现抑制GINS4的蛋白表达可有效促使G1、G1/S、S和G2/M期细胞发生铁死亡,尤其是其中处于G2/M期的细胞对铁死亡诱导剂Erastin的诱导表现最为敏感。
铁死亡是一种铁依赖性氧化,非凋亡形式的调节细胞死亡,由氧化还原稳态的破坏引起。最近的研究揭示了调节铁死亡的复杂细胞网络。GINS4是真核G1 / Scell循环的启动子,作为DNA复制开始和伸长的调节剂,但对其对铁死亡的影响知之甚少。
4月5日,中南大学基础医学院肿瘤研究所陶永光团队在知名期刊《Proceedings of the National Academy of Sciences of the United States of America》上发表研究论文“GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail”,研究发现GINS4参与了肺腺癌铁死亡的调控。在研究探讨DNA复制基因在LUAD中的作用时,研究人员发现抑制GINS4的蛋白表达可有效促使G1、G1/S、S和G2/M期细胞发生铁死亡,尤其是其中处于G2/M期的细胞对铁死亡诱导剂Erastin的诱导表现最为敏感。
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