Severe case of a condition called pitted keratolysis!

Pitted keratolysis is a superficial bacterial skin
infection that affects the soles of the feet, and less often, the palms of the hands. It is one of the causes of smelly feet. It is characterised by whitish skin and clusters of punched-out pits.

Pitted keratolysis is caused by several bacterial species, including corynebacteria, Dermatophilus congolensis, Kytococcus sedentarius, actinomyces and streptomyces.
The bacteria proliferate in moist conditions. The pitting is due to destruction of the corny cells (stratum corneum) by protease enzymes produced by the bacteria. The bad smell is due to sulfur compounds produced by the bacteria: thiols, sulfides and thioesters.

Treatment of pitted keratolysis requires the application of antibiotics to the skin such as benzoyl peroxide, clindamycin, erythromycin, fusidic acid, or mupirocin. Prevention efforts aim to keep the feet dry by using moisture-wicking shoes and socks as well as antiperspirants.
#医学生Medic##medicaltalks##皮肤科#

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